Management of Rhinitis Medicamentosa: A Systematic Review (2025)

Otolaryngology–Head and Neck Surgery

Volume 160, Issue 3 pp. 429-438

Review Articles

Shana M. Zucker,

Shana M. Zucker

Department of Otolaryngology–Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA

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Blair M. Barton MD,

Blair M. Barton MD

Department of Otolaryngology–Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA

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Edward D. McCoul MD, MPH,

Corresponding Author

Edward D. McCoul MD, MPH

  • [emailprotected]

Department of Otolaryngology–Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA

Department of Otorhinolaryngology, Ochsner Clinic Foundation, New Orleans, Louisiana, USA

Ochsner Clinical School, School of Medicine, University of Queensland, New Orleans, Louisiana, USA

Corresponding Author: Edward D. McCoul, MD, MPH, Department of Otorhinolaryngology, Ochsner Clinic Foundation, 1514Jefferson Hwy, CT4, New Orleans, LA 70121, USA. Email: [emailprotected]Search for more papers by this author

Shana M. Zucker,

Shana M. Zucker

Department of Otolaryngology–Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA

Search for more papers by this author

Blair M. Barton MD,

Blair M. Barton MD

Department of Otolaryngology–Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA

Search for more papers by this author

Edward D. McCoul MD, MPH,

Corresponding Author

Edward D. McCoul MD, MPH

  • [emailprotected]

Department of Otolaryngology–Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA

Department of Otorhinolaryngology, Ochsner Clinic Foundation, New Orleans, Louisiana, USA

Ochsner Clinical School, School of Medicine, University of Queensland, New Orleans, Louisiana, USA

Corresponding Author: Edward D. McCoul, MD, MPH, Department of Otorhinolaryngology, Ochsner Clinic Foundation, 1514Jefferson Hwy, CT4, New Orleans, LA 70121, USA. Email: [emailprotected]Search for more papers by this author

First published: 16 October 2018

Citations: 26

Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

This article was presented as a poster at the 2018 Triological Combined Sections Meeting; January 18-20, 2018; Scottsdale, Arizona.

Abstract

Objective

Rhinitis medicamentosa (RM) is a common condition resulting from overuse of topical nasal decongestants. Despite the prevalence in otolaryngologic practice, a clear treatment protocol has not been established. Our objective was to review the current published literature pertaining to the treatment of RM with the possibility of finding data that support one treatment over another.

Data Sources

PubMed, Embase, Cochrane, and Web of Science databases were examined for patients diagnosed with RM resulting from chronic use of topical nasal decongestants.

Review Methods

The PRISMA standard (Preferred Reporting Items for Systematic Reviews and Meta-analyses) was utilized to identify English-language studies reporting treatment of patients with the primary diagnosis of RM after chronic use of a topical decongestant. Outcome measures of interest included patient-reported symptom relief and objective parameters. MINORS criteria (methodological index for nonrandomized studies) were used to assess the quality of articles.

Results

A total of 350 articles were identified, 9 of which met final inclusion criteria for qualitative analysis. Outcomes defined in each publication were highly varied and relied on several unstandardized measures. The most commonly reported treatment option was topical nasal steroids, although overall there was limited evidence on which to base treatment recommendation.

Conclusions

There is not adequate evidence to develop a standardized treatment protocol for RM. The development of a uniform questionnaire, standard outcomes to be measured, and a method of assessing such outcomes is necessary. Prospective randomized controlled studies are warranted to determine the optimal treatment regimen following diagnosis of RM.

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Citing Literature

Volume160, Issue3

March 2019

Pages 429-438

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